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Flavonoid Supplements Prevent Impairment of Endothelial Function
Published February 20th, 2009
Itamar Medical, a company developing noninvasive diagnostic technology using the Peripheral Arterial Tone (PAT™) Signal, has announced the use of the company’s patented Endo-PAT2000 in the Carolinas HealthCare System’s study of the potential benefits of flavonoid supplementation on endothelial function.
The Endo-PAT2000 was used to measure participants’ endothelial function in a study designed to evaluate how flavonoid supplementation can prevent the adverse impact on endothelial function caused by a high-fat meal.
Various foods high in flavonoids such as black tea, dark chocolate, red wine and citrus fruits have been associated with lower risk for cardiovascular disease, and medical research conducted with foods high in flavonoids have demonstrated improvement in endothelial dysfunction, the earliest clinically detectable stage of cardiovascular disease.
Itamar Medical’s Endo-PAT2000 was used to measure endothelial function in 23 healthy volunteers before and after 4 weeks of flavonoid and placebo supplementation. According to Endo-PAT measurements, eating a high-fat meal produced an acute decline in endothelial function for all volunteers before supplementation, and after 4 weeks of placebo supplementation. However, Endo-PAT measurements indicated no similar acute decline in endothelial function from the consumption of a high-fat meal after 4 weeks of flavonoid supplementation. Study results indicate that flavonoid supplementation can reduce the acute impairment of endothelial function caused by a high-fat meal, adding to the growing medical literature on the long-term benefits of flavonoid supplementation on endothelial dysfunction and cardiac health. http://www.itamar-medical.com
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